Cryo-electron microscopy breaks a key barrier

Re:Cryo-electron microscopy breaks a key barrier by COGlory on Thursday June 04, 2020 @10:45AM (#23417239)

There aren't any. The way cryo-EM works is it images hundreds of thousands of copies of the molecule and uses those to construct a 3D model, in this case, with atomic resolution. However, a single micrograph doesn't necessarily contain atomic resolution.

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Re:Cryo-electron microscopy breaks a key barrier by natechols on Thursday June 04, 2020 @01:33PM (#23419399)

Haven't checked the article, but it's certainly possible the individual particle micrographs are archived somewhere. (But you're right, each will just look like a fuzzy gray blob.)

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Re:Cryo-electron microscopy breaks a key barrier by rezna on Thursday June 04, 2020 @02:09PM (#23419826)

No longer need for hundreds of thousands. The aim is for just few thousands in few hours to reach acceptable resolution.

The development goes real fast with both SW and HW.

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Re:Cryo-electron microscopy breaks a key barrier by COGlory on Thursday June 04, 2020 @04:27PM (#23421352)

Depends greatly on whether or not what you're imaging has symmetry.

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Re:Cryo-electron microscopy breaks a key barrier by rezna on Friday June 05, 2020 @04:11PM (#23433390)

You can see that the record tests are being done with apoferitin or gaba. It all depends on the improved qualiry of direct detection cameras, filters, things like afis, fringe free imaging, ... The innovation goes insanely fast.

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Re:Cryo-electron microscopy breaks a key barrier by perl4ever on Thursday June 04, 2020 @06:41PM (#23422837)

This is HN, everybody knows you can't use a 3D model to produce images, "pictures" as laypeople call them.

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Re:Cryo-electron microscopy breaks a key barrier by diegoperini on Thursday June 04, 2020 @12:03PM (#23418359)

Thanks for the explanation.

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