The touch-screen buttons in many cars often do change meaning, even if they don't change position within a given context.

I first experienced this on a Prius back in the mid-2000s, where the touch-screen was in one of several modes (climate, radio, navigation etc) and even if one can remember where the controls are, it's necessary to look before touching. That car had more physical buttons than is generally the case now and was still difficult to operate.