Sometimes developers distribute their software via Conda installs, in those cases they sometimes don't provide instructions on running other ways (eg using the pyenv environment which is my default. ). I'm ok with this, but when conda fails as sometimes happens, it can mean some digging to get the install to work.

I was thinking of my latest install, which was CRISPRESSO2, which installs via docker or bioconda... I was able to get it going, but it took a bit on some systems.. (Python 2.7 old libraries.. etc..) Docker didn't seem to work.

I like virtual env, but sometimes I feel I have to have a new environment for each piece of software I'm running, which feels weird.

https://github.com/pinellolab/CRISPResso2