I don't believe you can have that conversation effectively if each person gets to send one message per day due to timezone-induced lack of workday overlap.

Day 1 M> So, what do you think your next career move would be?

Day 2 E> I don't know. I really enjoy software engineering, but I think I'm ready to take on some kind of leadership role.

Day 2 M> OK, that's great. Do you need any kind of support before taking that on?

Day 3 E> I'm not sure what you mean.

Day 3 M> ...