Alterations in glutamate and the experience of ego dissolution with psilocybin

Re:Alterations in glutamate and the experience of ego dissol... by ketamine__ on Thursday May 28, 2020 @06:10AM (#23335552)

I agree with your statement on principle that we should make these drugs widely available when we find efficacy.

I disagree that we shouldn't try to separate psychedelic effects from therapeutic action. There is a body of research on ketamine metabolites. Some of these metabolites may have less psychedelic effects and more anti-depressant action.

I need to take ketamine almost every day. This means there are several hours when my ability to read, think, and remember things is impaired. I hope we are able to discover better drugs.

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Re:Alterations in glutamate and the experience of ego dissol... by dahfizz on Thursday May 28, 2020 @11:48AM (#23338666)

> This means there are several hours when my ability to read, think, and remember things is impaired. I hope we are able to discover better drugs.

I don't think people give this enough consideration. Tripping on mushrooms might be enjoyable to some, but having it as a regimented treatment means you are losing a lot of time where you cannot be productive, cannot enjoy the company of your sober friends and family, etc.

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Re:Alterations in glutamate and the experience of ego dissol... by luckydata on Thursday May 28, 2020 @01:58PM (#23340307)

The psychedelic effect IS the therapeutic action.

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