Sure, Spotlight has been around for at least a decade; it's the little magnifying glass at the right end of the main menubar. It definitely indexes PDFs with a text layer as well as other document formats; I've been running them through OCR for ages and have 28,000 in my records. You can also install extensions for other formats.

It indexes your whole disk; if there's a limit as to how many files it will index, I've yet to reach it. I checked Apple's developer documentation, and they don't mention one.