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Re:Ask HN: What startup/technology is on your 'to watch' list? by lvs on Friday May 22, 2020 @10:24PM (#23279272)
> UV light treatment of blood.

What? No... No don't do this. This is a discarded idea from the era before molecular biology, and it was discarded for very good reason.

Re:Ask HN: What startup/technology is on your 'to watch' list? by skmurphy on Friday May 22, 2020 @11:13PM (#23279551)
Opportunity can come from ideas that are correct but not generally accepted as correct.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783265/

If it were to work it would be a useful new modality. I am not promoting it, but it's on my "watch list" due to efforts by AYTU at Cedars Sinai.

Re:Ask HN: What startup/technology is on your 'to watch' list? by bearsnowstorm on Saturday May 23, 2020 @06:23AM (#23281756)
In my experience the commonest current mainstream use of this is for Sezary Syndrome / mycosis fungoides (cutaneous T-cell lymphoma). See for example:

https://my.clevelandclinic.org/health/articles/8493-mycosis-...

Re:Ask HN: What startup/technology is on your 'to watch' list? by lvs on Saturday May 23, 2020 @01:51AM (#23280296)
Opportunity to give people leukemia. These ideas are at a prehistoric level of biology. We're way beyond this silliness now.
Re:Ask HN: What startup/technology is on your 'to watch' list? by skmurphy on Saturday May 23, 2020 @04:06AM (#23280991)
I am talking about work being done in clinical trials at reputable medical clinics. They may be mistaken but I don't think it's "silliness." Here is a recent clinical trial evaluating UVBI https://www.tandfonline.com/doi/full/10.1080/2331205X.2019.1...

Of course there are many other mainstream treatments that came from somewhat oddball ideas: Sister Kenney's treatments for polio, the Nobel prize winning discovery by Barry Marshall and Robin Warren that ulcers were caused by bacteria (H. Pylori), the use of leaches for treatment of venous congestion after surgery, and the use of maggots for wound debridement.

Re:Ask HN: What startup/technology is on your 'to watch' list? by lvs on Saturday May 23, 2020 @05:10AM (#23281377)
It should never have been signed off on by an IRB. It is irresponsible and horrific that this has been trialed on people in this century.
Re:Ask HN: What startup/technology is on your 'to watch' list? by skmurphy on Saturday May 23, 2020 @02:24PM (#23285164)
I suspect this may be a case of "the dose makes the poison."

You may be generalizing from a specific experience or specific experiment and rejecting a modality that may have significant efficacy.

It's hard to tell what you are basing your assertions on because you offer no specifics. My "watch list" interest is based on the number of positive experimental results and ongoing investigations of the technique.

Re:Ask HN: What startup/technology is on your 'to watch' list? by ianai on Saturday May 23, 2020 @05:43AM (#23281566)
Any specific objections to the research links provided?