The hope of something like this isn't to replicate Skype (the UI and behaviors) in an "open" form but to set the stage for new and different communications tools that wouldn't have been possible.

Some random thoughts on scenarios where this might make sense over Skype

1. You want to make a game that includes voice chat.

2. You're building something that's more a one-way flow of audio (like a baby monitor).

3. Self hosted Twilio type services.

4. An in house/office intercom system.