If you're approaching that point, you already are going to need an analytics pipeline, a search DB, etc, because maintaining ever growing indices will kill your latency. You probably can get away with aggregations for a bit longer, but if the number of rows you aggregate is growing too, eventually you will need to come up with something and the way you do that with Dynamo off a stream isn't a bad way to go about it with MySql either.

Looking at the tables I have access to, they all come under 5ms for both read/write. This is the same ballpark as our MySql apps for similar style queries (i.e. not aggegrations).

Sadly my favorite reason to use Dynamo is political, not technical. Since it somehow is not classified as a database at my company, the DBAs don't 'own' it. So I don't have to wait 2-3 months for them to manually configure something.

Conway's law strikes again.