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Re:America’s Havana: Thousands Say “Ciao” to San Francisco by ashtonkem on Tuesday May 12, 2020 @08:17PM (#23161838)
Ideally no. But a lot of them are also flat beds and cattle cars that’ll let air through them when totally empty.

I’m assuming that wind is taken in as a factor when deciding what stock to send where though.

Re:America’s Havana: Thousands Say “Ciao” to San Francisco by refurb on Tuesday May 12, 2020 @08:36PM (#23161999)
You do hear of derailments due to wind sometimes for empty freight cars.

https://en.wikipedia.org/wiki/List_of_wind-related_railway_a...

Interesting stuff!