For that matter: Sciter supports use of native platform (or custom) native windows or widgets. For different reasons an combinations. I saw cases when even Qt widgets were used as DOM elements in Sciter controlled main window. So you can get best of two worlds - flexibility of HTML/CSS (rendering, layout managers) and native UI behavior and look.
Can the native UI framework do multiple windows? - Then React-Native can do multiple windows.
Rendering to a windows that isn't owned by the framework is what React-Native refers to as Brownfield apps. This is absolutely supported. For instance, Microsoft Office is using React-Native for some parts of their UI in Android, iOS, Windows and macOS. And the Office window is not created or owned by react-native.