I think the most that can be said is that is that it is uncertain the degree of influence these (well supported) sex differences in general temperament and preferences have on the specific jobs of software engineering and tech leadership.

However, just because the science is not settled on the subject does not mean one cannot put forth a reasonable hypothesis.

And for the record, the idea that these sex differences have no influence on inclinations towards these specific jobs is also a hypothesis.

Damore may be wrong about the nature of that influence, but I think most people would be surprised if the "no influence" hypothesis was true.