I use Dvorak exclusively and echo the other comment -- I'm not sure that it has made a dramatic difference in my speed, but it is much more comfortable! Your hands sit neatly on the home row, and do not have to reach much. The only downside is that I use vim and after many years of Nethack am pretty good at hjkl movement, and I can't even take advantage! :( Definitely something to consider though if you want to switch and are a vim user.