Definitely. The Bay Area is a bit tougher to get out of really expensive housing depending upon where you work. But I'm (at rush hour) something like 90 minutes out of Boston whether driving or rail/subway. And housing is, if not depressed Midwest cheap, pretty reasonable in many towns that far out.

That is, as you say, pretty brutal daily--which I never really had to do even when I worked in the city. But it's only a mild PITA once a week or so.

Not to mention that if you're in a day a week for specific meetings (vs it being your "office" the expectations about when you will arrive there are different. You may be able to travel during quieter hours which can be faster and less stressful.