Re:Human body-on-chip platform could speed up drug testing
by alevskaya on Thursday April 30, 2020 @05:09AM
(#23028924)
I worked as a genetic engineer in human cell therapy: developmental biology doesn't really work that way. You can't just "decephalize" without causing massive secondary effects in body development and maturation - the nervous system is very much a central part and organizer of animal development, and also centrally important in a lot of the physiology you want to test when doing drug trials! And good luck keeping decephalized animals alive long enough to harvest outside a sterile lab. You don't need to be an edgelord billionaire to make a difference, but you'd benefit by learning more biology.
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Re:Human body-on-chip platform could speed up drug testing
by echelon on Thursday April 30, 2020 @05:18AM
(#23028971)
I don't have firsthand experience, but it seems like you could play with ectoderm development in conjunction with manual surgical techniques. Program the neural tube cells to die at a certain stage of development or when treated with certain media.
I think keeping the body alive will pose a much greater problem than preventing the brain from developing.