I am not sure if it is a good idea to host SFUs* fairly centrally in cloud data centers. Wouldn't it be cheaper to build a network of SFUs that deal with traffic as locally as possible? That keeps backbone traffic low and and cloud traffic costs sane at the expense of having to find all these colo sites. I reslly have no if AWS or GCP could even handle all that incoming and outgoing traffic in theory.

*SFU: selective forwarding unit - the node in a video conference call that receives and resends all the video streams between participants.