No, the science doesn't "support shelter-in-place", because science in itself doesn't support any particular policy. Instead, the science is simply predicting a certain number of deaths or burden on the healthcare system, and certain public-health officials are recommending policy to minimize number of deaths, because their sole priority is to save human lives. However, someone else could look at that same science predicting a certain number of deaths, and say that such a number of deaths is an acceptable sacrifice and a policy of reopening the economy can be pursued.