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A comment on The San Francisco Bay Area shelter-in-place order is being extended through May. Parent comment

Re:The San Francisco Bay Area shelter-in-place order is bein... by exmadscientist on Monday April 27, 2020 @05:54PM (#23000565)
Unfortunately, yes. Consider the common cold: yes, it does mutate fast, but the other big barrier to producing a vaccine is that immunity to it doesn't last very long at all. So if COVID-19 immunity truly doesn't last long, that's a problem.

I doubt this is likely to be the case, though. Antibodies to SARS seemed to have long lifetimes (several years), and COVID is likely to be similar. It is certainly possible that for some people, immunity fades much faster for reasons specific to that person, and that may be what is being picked up in these reports.

It is also possible it's just shoddy lab work. There has been a ton of that going around lately, and it's not just caused by pressure from the situation. Not all scientists are equally competent....

(Disclaimer: my knowledge of immunology is likely little better than yours, but I did at least used to be a Real Scientist in a different field.)

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Re:The San Francisco Bay Area shelter-in-place order is bein... by jacquesm on Monday April 27, 2020 @06:58PM (#23001158)
The reason that antibodies to SARS have long lifetimes is because it is a much worse hit than COVID-19 in most cases, you can take the CFR as proof of that. Harder hit to the immune system but you survive: immunity will last longer is a good rule of thumb.
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