You get used to it, but it is fair to call it a significant time cost. When we take the Tesla, we stop halfway to grandma's house for 20-30 minutes, then we stop again on the way back. Sure, it's a convenient break for the kids to go pee, but it's only a 2.5 hour trip each way and in our F150 we'd do the whole thing without any fuel or pee stops and it'd be fine. So it costs a solid hour, or 20% more time.