FWIW, from having looked into this, there are two main challenges:
(1) Security - How to avoid the customer becoming superuser by using specifically crafted extensions. In practice this is mostly a defense in depth scenario, since you're running inside a VM already anyway.
(2) Maintenance / Support / SLA - If customers load a broken extension and that causes the server to crash, does the provider still give an SLA? Where to draw the line / how to evaluate this when support tickets get opened?
Both of these could be solved (I think) if there was a better sandboxing mechanism.
Really the issue here is that once you're at the C extension / shared library level, you can do pretty much anything, and thats really hard to support as a Database-as-a-service provider.
[1] https://github.com/postgres/postgres/tree/master/contrib/ltr...
[2] https://github.com/microo8/plgo