Severe acute respiratory syndrome coronavirus 2 is the causative agent of the 2019 novel coronavirus disease pandemic. Initial estimates of the early dynamics of the outbreak in Wuhan, China, suggested a doubling time of the number of infected persons of 6–7 days and a basic reproductive number (R0) of 2.2–2.7. We collected extensive individual case reports across China and estimated key epidemiologic parameters, including the incubation period. We then designed 2 mathematical modeling approaches to infer the outbreak dynamics in Wuhan by using high-resolution domestic travel and infection data. Results show that the doubling time early in the epidemic in Wuhan was 2.3–3.3 days. Assuming a serial interval of 6–9 days, we calculated a median R0 value of 5.7 (95% CI 3.8–8.9)
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by endorphone on Friday April 10, 2020 @11:23AM
(#22833943)
The CDC is now estimating the R0 at 5.7, which is really high, and seems much more likely given the extremely rapid spread in areas like NYC.
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by fxj on Friday April 10, 2020 @11:46AM
(#22834196)
Abstract
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by xenonite on Friday April 10, 2020 @12:07PM
(#22834399)
So, what is your verdict? This only confirms the OP’s claim that the R0 might be much higher than expected.
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by fxj on Friday April 10, 2020 @12:40PM
(#22834710)
Just wanted to give the information. The facts speak for themselves.
Re:SARS-CoV-2 titers in wastewater are higher than expected ...
by xenonite on Friday April 10, 2020 @08:58PM
(#22838881)
Ok, considering that the OP was heavily downvoted without anyone voicing concerns, I am frankly not so sure about that.
Honestly? An R0 of 2-3 is frankly not that high.
If grocery shopping were a huge risk, and people spread the disease before being symptomatic, you’d expect a single sick individual to infect way more than just 2-3 people on average.
Compare with measles’ 12-18 R0. That’s high.