"No meme" could suggest "Don't try to shortcut and assume things about <some statement>" because we have realized that memes are a lazy way to transmit ideas without research? Disinformation seems to be the consequence of exponentially increasing bandwidth for all....
But now that you have clarified your intended description of your twitch.tv banter encounter - it makes sense. "No meme" is a synonym for "no joke". Joking exists as an informal method of addressing (challenging?) a certain idea, and laughter reporting (lol, rofl, lmao, etc) confirms reception. Twitch seems to be a social arena for leisure, where workers exchange ideas and bond after-hours over a shared virtual experience with allotted "free" time (virtual/comfortable, therefore abundance of "joking" because nothing is at stake). But when a user desires to "get down to business" and submit concepts to the local chat space because her/his mind has been prompted to consider more pressing issues, then the surrogate-preface-phrase "no meme" can be applied in order to summon the "real world" empathy of connected compatriots also confined to the same virtual space.
Now, the modern "career politician" may be one who can say many words and appear reasonable and educated [3] despite having only spent his/her life in classrooms and "seats" of progressing political levels.
I'm assuming that for the past few decades, POTUS has been just a ceremonial role for mass media consumption. If you need a metaphor (American football), the POTUS is a lineman, the vice POTUS is the quarterback, (Queen Amidala and Handmaiden Padme) the coach/offensive&defensive coordinator/ team owner are people you will never see on a screen (sidelines).
[1] https://en.wikipedia.org/wiki/Antoninus_Pius
[2] https://en.wikipedia.org/wiki/Lucius_Quinctius_Cincinnatus
[3] https://www.huffpost.com/entry/ted-cruz-green-eggs-and-ham_n...
I wonder if people will gradually become less quick and witty over time with this increasingly standard mode of communication.
But there are benefits to be reaped from our ebb & flow of commenting and pondering throughout our day.
I know that these are akin to "loading time" phrases that people habitually use to interject into a talkative group or to introduce their vocal tone before the meat content is transmitted to multiple listeners. But it is the nature of the phrases that suggest the existence of lies or an exaggerated reality that fascinates me (you had me thinking of honesty or lying before you had me thinking about the nature's ninja assassin metaphor).
I do not see it as a bad thing - this is only our natural response (clues are in these "harmless" phrases inserted into everyday conversation) to a few decades of concerned tax paying citizens being fed questionable or far-fetched content from their media outlets as a method of attempted economic subjugation?