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Re:We Made One Gram Of Remdesivir by est31 on Sunday April 05, 2020 @03:51AM (#22784369)
There is no RNA cloning machinery in our cells. The RNA is instead copied from the DNA in the nucleus. Viruses like the coronavirus actually bring their own RNA cloning machinery that's assembled by the cell. Remdesivir only blocks the RNA cloning proteins of the virus.
Re:We Made One Gram Of Remdesivir by rocqua on Sunday April 05, 2020 @04:17AM (#22784446)
Doesn't that mean that Remdesivir would essentially defeat _all_ RNA viruses? Or is the effectiveness dependent on the exact RNA cloning mechanism used by the virus?
Re:We Made One Gram Of Remdesivir by rwmj on Sunday April 05, 2020 @05:24AM (#22784673)
Yes, it was originally invented to treat ebola, but it's thought to have general antiviral properties against RNA viruses.
Re:We Made One Gram Of Remdesivir by lisk1 on Sunday April 05, 2020 @05:44AM (#22784746)
There are a lot more RNA virus specifically targeting antivirals surprised that most of them are not yet tested.
Re:We Made One Gram Of Remdesivir by malwarebytess on Sunday April 05, 2020 @06:07AM (#22784835)
sounds like we should get on it
Re:We Made One Gram Of Remdesivir by rwmj on Sunday April 05, 2020 @11:56AM (#22786294)
According to this radio programme[1] I was listening to at the weekend, scientists have been warning about the potential of coronaviruses to cause a pandemic for a long time, and saying we should work on general antivirals for them. Obviously that didn't happen.

[1] https://www.bbc.co.uk/programmes/m000gvd1

Re:We Made One Gram Of Remdesivir by koheripbal on Sunday April 05, 2020 @04:49PM (#22788599)
Didn't it? The one we're talking about was developed to fight the last two Coronaviruses.
Re:We Made One Gram Of Remdesivir by vikramkr on Sunday April 05, 2020 @03:15PM (#22787755)
Yep. This is the same drug they tried to deploy against Ebola, and that's why they think itll be useful for such a wildly different drug virus here as well