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Re:Lyme disease bacteria eradicated by new drug in early tests by zxexz on Friday April 03, 2020 @10:50AM (#22769733)
I think you raise an excellent point, that many don't really think about. Detection is hard, and research on microbes is hard if you can't grow them in-vitro. There is research in this space. A few years ago, I had a lecture from Slava Epstein, a professor who has made some major inroads in this space[0].

[0] https://experiments.springernature.com/articles/10.1038/npro...

Re:Lyme disease bacteria eradicated by new drug in early tests by projektfu on Saturday April 04, 2020 @10:23AM (#22778363)
I assume you’re aware but I wanted to mention that there are many detection methods besides culture. Electron microscopy, fluorescent DNA probes, histochemistry, etc.
Re:Lyme disease bacteria eradicated by new drug in early tests by y-c-o-m-b on Friday April 03, 2020 @02:43PM (#22772711)
Detection is hard indeed. Here is an interesting research on patients with neurological disabilities though normal imaging (MRI) results, but abnormalities found when inspected using diffuse tensor imaging: https://nn.neurology.org/content/5/3/e456