Please read the study and the CDC web page you're linking to. They don't support your point.
From the CDC link you provided:
> Doxycycline (100 mg orally BID X 14 days) is generally recommended for prophylaxis in adults.
From the study you linked to above:
> A single 200-mg dose of doxycycline given within 72 hours
The CDC recommends a 14-day course of twice-daily dosing (BID = twice daily). It has no relationship to the single-dose NJEM study you linked to above.
"In areas that are highly endemic for Lyme disease, a single prophylactic dose of doxycycline (200 mg for adults or 4.4 mg/kg for children of any age weighing less than 45 kg) may be used to reduce the risk of acquiring Lyme disease after the bite of a high risk tick bite."
You can also see their guidelines for doctors here:
https://www.cdc.gov/lyme/resources/FS-Guidance-for-Clinician...