No. Almost every medium and large city in the United States was built because of its access to water and shipping. New York, Chicago, San Francisco, Houston, PORTland, Boston, Pittsburgh, Cleveland, Charleston, and on and on and on.

Even smaller cities like Minneapolis, Buffalo, Sioux Falls, Albany, and hundreds more are located where they are because waterfalls and rapids made them the farthest extent of water travel before rapids or waterfalls or other hazards made the route too difficult.