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Re:About that Hydroxychloroquine for Covid-19 trial by lez on Monday March 23, 2020 @09:23AM (#22663844)
Another anti-malaria drug, methylene blue had been proven to work against coronavirus in blood plasma in 2005 [1].

It is used in photodynamic therapy to selectively kill some viruses (see below) / bacteria (e.g. mycoplasma) [2].

When entering the bloodstream, it binds selectively to the nucleus of the viruses it is effective against. It's the same mechanism why it's effective as a dye to stain microbes under microscope. Methylene blue best absorbs light at 660nm wavelength, which at the same time penetrates into human tissues deeply. When light is absorbed, methylene blue disintegrates to harmless molecules while releasing reactive oxygene species, killing the virus.

It is a very safe drug, so the same logic that bsaul mentioned could be applied, and therefore would be a responsible move. It is also beneficial to mitochondria and effective against fungus.

[1] https://europepmc.org/article/cba/518857 [2] https://www.sciencedirect.com/science/article/abs/pii/S15721...

Re:About that Hydroxychloroquine for Covid-19 trial by hprotagonist on Monday March 23, 2020 @10:56AM (#22664678)
it also literally turns your bodily emissions blue, needs to be administered intravenously, and has some ugly side effects:

Common side effects include headache, vomiting, confusion, shortness of breath, and high blood pressure.[1] Other side effects include serotonin syndrome, red blood cell breakdown, and allergic reactions.[1] Use often turns the urine, sweat, and stool blue to green in color.[3]

Re:About that Hydroxychloroquine for Covid-19 trial by lez on Monday March 23, 2020 @12:15PM (#22665414)
These side effects occur in extremely high doses, much much higher than the effective dosage.

It doesn't need to be administered intravenously (only for methemoglobenia) - although more effective that way.

serotonin syndrome, rbc breakdown and allergic reactions occur when you drink a glass of what few drops are enough.

As said, it is extremely safe drug in low dosages (4-16 drops of 0.1% solution).

Edit: Also see the Kevin Rose Show episode https://podcast.kevinrose.com/dr-peter-attia-longevity-compo... starting @ 1:16:20

Re:About that Hydroxychloroquine for Covid-19 trial by tootie on Monday March 23, 2020 @04:58PM (#22668678)
Is there a reason these drugs may have value fighting variations of coronavirus and not other virii? What's the suspected mechanism?
Re:About that Hydroxychloroquine for Covid-19 trial by nikolay on Monday March 23, 2020 @08:33PM (#22670521)
Many life extension folks use methylene blue daily for years.