It's likely. The body will be less likely to have undergone the immune response to generate antibodies of its own. Additionally, as the immune response develops, the antibody affinity to its target is refined through a process called "affinity maturation", so any antibodies which are produced might not have high affinity and hence result in a weaker immune response.

Treatment with antibodies might be useful as an immediate fix, but vaccination or infection and the development of a proper immune response is the long term requirement for resistance.