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Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by cowmoo728 on Saturday March 14, 2020 @07:10AM (#22574476)
I believe I have it although I haven't been tested yet. I'm a healthy and physically active 28 year old. I have a high fever, general body aches, difficulty swallowing, dry painful cough. This is the third day of symptoms with no improvement. No pressure or tightness in my chest as of yet.

However, if I have it, my wife probably has it too. Her only symptoms are a mild sore throat and an ache in her back. It's much less severe than mine.

I had the bad luck of getting swine flu in 2009 and this is just as bad.

Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by FreshEconomist on Saturday March 14, 2020 @09:15AM (#22575042)
I think I absolutely misrepresented what I think. I didn't mean for it to come off that it wasn't more serious than a normal cold. I meant that many won't be affect more than that,. However the ones that get more sever cases/more exposure are at high risk, not to mention the older populace in general. I'm absolutely terrified for everyone right now.
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by delhanty on Saturday March 14, 2020 @07:16AM (#22574495)
It's not just live or die you know. Reduced quality of life is a possible out come too:

>Similar to patients with SARS-CoV and MERS-CoV, some patients with 2019-nCoV develop acute respiratory distress syndrome (ARDS) with characteristic pulmonary ground glass changes on imaging. In most moribund patients, 2019-nCoV infection is also associated with a cytokine storm, ... in those who survive intensive care, these aberrant and excessive immune responses lead to long-term lung damage and fibrosis, causing functional disability and reduced quality of life.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by forkexec on Saturday March 14, 2020 @07:30AM (#22574538)
Yep. Both SARS viruses can damage the lungs. And short of lung transplantation and likely a lifetime of anti-rejection medications, lost lung function doesn't return.
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by lsiebert on Saturday March 14, 2020 @07:21AM (#22574507)
No, this is worse than a cold. Worse than the flu as well. For 18 to 49, the death rate for flu last year was 1.8 per 100,000 people. Corona virus's death rate is unknown but even among 20 somethings they are talking about an estimated .2% death rate. That's 200 per 100,000 https://www.cdc.gov/flu/about/burden/2018-2019.html
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by endorphone on Saturday March 14, 2020 @07:26AM (#22574520)
Further, that assumes that the healthcare system can perform heroic efforts. In cases where the system is overloaded, such as seen in Italy, mortality numbers can get much worse. Now add that some/many patients have lung scarring that can hold with them for life.

With all of the information available demonstrating that it clearly is pretty serious, I've come to identify people downplaying it as essentially the exercising of wishful thinking: If I tell everyone it's nothing, maybe it will be.

I hope it's nothing. At the same time I understand the responses that have occurred.

Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by speleding on Saturday March 14, 2020 @08:55AM (#22574943)
That's a bit alarmist. Based on the numbers from Wuhan, where the disease has progressed furthest and the numbers are most clear, it's about 5 times worse than a seasonal flu. There is considerable uncertainty at this stage, of course, but the lower numbers look more realistic. Source: https://www.economist.com/international/2020/03/12/fatality-...
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by FreshEconomist on Saturday March 14, 2020 @09:16AM (#22575053)
Yeah what I typed came across badly, I wasn't intending to download like it seemed from that comment.
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by pritovido on Saturday March 14, 2020 @07:24AM (#22574513)
Most children can be host without suffering it and transmit it to other people.

For middle age people, if you are unlucky and get other virus at the same time(because you met with lots of people in a place), like the flu, it can be extremely dangerous.

Last year I catched two virus at the same time and it was so painful. My body reacted too strong with an autoimmune reaction, attacking my own body, my joints, my muscles.

It took me two months to properly recover, and I live a very healthy lifestyle. I sleep and eat well and exercise. The doctor told me that someone in the same situation that smokes for example could develop lots of complications.

Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by forkexec on Saturday March 14, 2020 @12:43PM (#22576606)
Get a flu shot, wash your hands, and stay away from large groups and don't exercise to exhaustion during periods of peak transmission.
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by RivieraKid on Saturday March 14, 2020 @07:00AM (#22574439)
It's definitely worse than a cold, the symptoms of a cold are very mild, for me it's usually painful swallowing, runny nose and slight and short-term increase in temperature and tiredness.
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by giu on Saturday March 14, 2020 @07:20AM (#22574504)
Absolutely. From the WHO page [0]

> Common signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death.

The problem is that some people forget that between "common signs" and "severe cases" there's a vast area of very uncomfortable symptoms until you get to the severe cases, and we're currently still learning about this very gray area.

Just yesterday the following link was posted on Hacker News: "Coronavirus: Some recovered patients may have reduced lung function", https://news.ycombinator.com/item?id=22568100

[0] https://www.who.int/health-topics/coronavirus

Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by andy_ppp on Saturday March 14, 2020 @06:57AM (#22574427)
We don’t know enough about it to be sure of making sweeping statements like this...
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by woofie11 on Saturday March 14, 2020 @06:54AM (#22574419)
... no. Unless you're a child, it's not a cold.

Good shot of ending up in the ICU.

Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by dmos62 on Saturday March 14, 2020 @06:55AM (#22574422)
Anyone has sources?
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by choeger on Saturday March 14, 2020 @06:58AM (#22574431)
The numbers vary massively but I have seen a number of about 20% hospitalized cases. This includes the elderly and people with preconditions. But still, you would not want to develop any pneumonia when your local hospital is running over its capacity.
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by forkexec on Saturday March 14, 2020 @12:45PM (#22576630)
It's a given that American hospitals will be running out of ventilators, beds, and nurses will be stretched too thin. And if you need an ECMO and/or organ transplant in the near future, good luck with that.
Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by greatest-ape on Saturday March 14, 2020 @07:07AM (#22574456)
Unsurprisingly, smoking seems to be a huge risk factor [1]: “[..] the multivariate logistic analysis indicated that age (OR, 8.546; 95% CI: 1.62844.864; P = 0.011), history of smoking (OR, 14.285; 95% CI: 1.57725.000; P = 0.018), maximum body temperature at admission (OR, 8.999; 95% CI: 1.03678.147, P = 0.046), respiratory failure (OR, 8.772, 95% CI: 1.94240.000; P =0.016), albumin (OR, 7.353, 95% CI: 1.09850.000; P =0.003) and C-reactive protein (OR, 10.53; 95% CI:

1.22434.701, P = 0.028) were risk factor for disease progression [Table 4].”

[1] https://journals.lww.com/cmj/Abstract/publishahead/Analysis_...

Re:A human monoclonal 1 antibody blocking SARS-CoV-2 infection by thatswrong0 on Saturday March 14, 2020 @07:09AM (#22574466)
https://miro.medium.com/max/3660/1*-O84hhKDRHmgMVAslvgj-Q.pn...

Here's a chart made from a study in China. It's actually a bit unclear, but I'm assuming it's 18.5% of confirmed cases that require hospitalization. Now, the question is how many of those that got sick at all got confirmed in China, and how many people presented symptoms (those are unknown).

So it seems like it's less than 18.5%. On top of this, Chinese men are heavy smokers and the air quality in China is pretty terrible, so that may play a part as well.