Everyone will eventually get one of the mutations. [1] Maybe a vaccine will cover all of them some day. In the mean time, everyone, especially those with pre-exisiting conditions should be focusing on removing burdens from their immune system (sugar, carbs, anything that spikes insulin), getting a LOT of sleep, and ensuring they are not deficient in D3, Zinc, L-Glutamine, Magnesium, well, all the essential minerals, vitamins and enzymes. I have not had a vaccine since the 1990's and I have only noticeably had the flu twice (h1n1, h3n2) and even then it just made me gassy. I went home as a courtesy to my coworkers. I have not had a cold in 15 years.

[1] - https://nextstrain.org/ncov