Sucralose with carbohydrates may blunt the body’s ability to metabolize sugar

Re:Sucralose with carbohydrates may blunt the body’s ability... by matthewdgreen on Tuesday March 10, 2020 @10:59AM (#22535981)

There have been studies where mice were fed a diet of various natural and non-caloric sweeteners. The mice were monitored for blood sugar levels and cholesterol as well as other measures. The mice who ate all three of the most popular artificial sweeteners had worse outcomes on several measures. There is some additional evidence that the effect is largely due to the sweeteners' effect on the composition of gut bacteria. I can't tell you if this holds up (or if it holds for humans) but aspartame does not seem to be harmless in these studies.

2: https://www.businessinsider.com/artificial-sweeteners-aspart...

Link to one actual study: https://www.mdpi.com/1420-3049/23/2/367

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Re:Sucralose with carbohydrates may blunt the body’s ability... by mohaine on Tuesday March 10, 2020 @12:40PM (#22536988)

> The dose (0.75 mg/kg body weight/day) > was 2.5× human allowed daily intake (ADI) (0.3 mg/kg body >weight/day) for neotame set by the U.S. FDA.

Neotame is 8000 * sweeter than sugar so this is the sweetness equivalent of 0.6 Kg of sugar a day or 2,348 calories for a 100kg human. This is also 8.4 * the average daily sugar consumption in the US.

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