I've never used this before, but I suspect this is exactly what you would want to use if you were on .NET and building latency-sensitive systems that see daily reboots:

http://tooslowexception.com/zero-garbage-collector-for-net-c...

If I was building something that was on a short fuse like this, I'd also be using structs and stack allocation as much as humanly possible before leaning onto the "having tons of physical memory" crutch. I feel like virtual memory could cover your ass for a small period of time before the whole thing started to grind to a halt.