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A comment on SARSCoV2 cell entry depends on ACE2 and TMPRSS2, blockable by protease inhibitor. Parent comment

Re:SARSCoV2 cell entry depends on ACE2 and TMPRSS2, blockabl... by snapetom on Friday March 06, 2020 @04:05PM (#22507285)
Thank you very much for the info and taking a look at it!
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Re:SARSCoV2 cell entry depends on ACE2 and TMPRSS2, blockabl... by rolph on Friday March 06, 2020 @05:18PM (#22507864)
basically ACE2 is a regulator that converts between angiotensin II <--> angiotensin 1,7

these have opposite effects , angiotensin II is a vaso-constrictor, thus increases blood pressure.

angoitensin 1,7 is a vaso-dialator, thus decreases blood pressure. so there is an equilibrium state of the two established by ACE2. this is something that ACE inhibitors or ARB blockers dont directly influence.

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