Coronavirus Spike Protein Binder Design

Re:Coronavirus Spike Protein Binder Design by DrAwdeOccarim on Tuesday March 03, 2020 @08:49AM (#22474381)

There is already stuff like this out there: https://www.biorxiv.org/content/10.1101/2020.02.01.929976v2....

Also, it appears as though convalescence therapy is working (i.e., treating people with the plasma from recovered patients) https://www.straitstimes.com/asia/east-asia/china-seeks-plas... https://news.yahoo.com/chinese-doctors-using-plasma-therapy-...

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Re:Coronavirus Spike Protein Binder Design by changoplatanero on Tuesday March 03, 2020 @09:12AM (#22474541)

Why cant they just extract the protein from the coronavirus?

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Re:Coronavirus Spike Protein Binder Design by DrAwdeOccarim on Tuesday March 03, 2020 @11:09AM (#22475694)

They can and are working on it/have already done it. The key then is to make it in large quantities. One way to avoid needing to make the protein is to deliver mRNAs for the heavy chain and light chain of the antibody. This would be faster, but it is not a proven technology so it's unlikely to work anytime soon (<1y) so convalescence treatment is much easier to do since blood transfusions are super common and well established.

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Re:Coronavirus Spike Protein Binder Design by fredgrott on Tuesday March 03, 2020 @11:16AM (#22475770)

did they not have the same problem in doing the aids vaccine?

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Re:Coronavirus Spike Protein Binder Design by wbl on Tuesday March 03, 2020 @11:22AM (#22475864)

There isn't an HIV vaccine.

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Re:Coronavirus Spike Protein Binder Design by letitgo12345 on Tuesday March 03, 2020 @10:09AM (#22475000)

I doubt it's easy to isolate

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