Re:Human gut bacterial enzyme ingests L-dopa and converts it...
by eganist on Thursday February 20, 2020 @07:17PM
(#22379875)
Interesting.
L-dopa appears to have L-Tyrosene as a precursor, which can be found in Casein (present in cheese) or synthesized from Phenylalanine (a metabolic byproduct of Aspartame).
Edit: The phe->tyr connection in the context of a gut biome capable of converting l-dopa to dopamine is dubious, though, because I'd assume phe->tyr synthesis would likely not take place in the gut, rather beyond it, in mammals. So uh, maybe just cheese?
Anyway, I'm not an organic chemist. I can't even remotely pretend to be qualified to connect those dots. But if my anecdotal/personal experience says anything: breaking my aspartame habit has been an utter nightmare when I switched to keto, and I still love cheese. I drank well over two liters of diet coke a day for years, and I still go through cheese like air.
I invite corrections from the experts here. Dead certain I got something wrong. All I know is I have a hideous addiction to certain foods and anything minting dopamine in my gut would surely invite my curiosity.
L-dopa appears to have L-Tyrosene as a precursor, which can be found in Casein (present in cheese) or synthesized from Phenylalanine (a metabolic byproduct of Aspartame).
https://en.wikipedia.org/wiki/L-DOPA
https://en.wikipedia.org/wiki/Tyrosine --casein in intro pgh
https://en.wikipedia.org/wiki/Tyrosine#Biosynthesis --phenylalanine
Edit: The phe->tyr connection in the context of a gut biome capable of converting l-dopa to dopamine is dubious, though, because I'd assume phe->tyr synthesis would likely not take place in the gut, rather beyond it, in mammals. So uh, maybe just cheese?
Anyway, I'm not an organic chemist. I can't even remotely pretend to be qualified to connect those dots. But if my anecdotal/personal experience says anything: breaking my aspartame habit has been an utter nightmare when I switched to keto, and I still love cheese. I drank well over two liters of diet coke a day for years, and I still go through cheese like air.
I invite corrections from the experts here. Dead certain I got something wrong. All I know is I have a hideous addiction to certain foods and anything minting dopamine in my gut would surely invite my curiosity.