I use my weekly 1:1 to brainstorm, sometimes to vent, and to discuss anything on the near horizon that affects my job, my pay, or life in MegaCorp generally.

I do not use it to rock the boat. Advice to younger employees: if you want to rock the boat, do it when your manager is not taking notes. :-)

(And I have a really good manager, so not assuming any malice anywhere.)