Or you could globally remap them to the Quake-controls and do ctrl+shift+E to pause, next and previous with W and S, 5 sec forward/backward with A/D and on/off with Q.

Nothing like fragging your friends while playing loud music but able to skip a song if it doesn't fit the moment, all without even flipping active window. Never looked at another player because of this function.

Just had to adapt with ctrl+shift+B for next song since S was hard bound in some game.