Re:A prospective Alzheimer’s trial reports
by atombender on Monday February 10, 2020 @01:22PM
(#22291723)
That clinical trials list doesn't mention the GAIN phase 2/3 trial [1] [2] currently underway to test COR388 from Cortexyme [3].
It's a small molecule that targets gingipains, cysteine proteases of the P. gingivalis, a periodontal pathogen responsible for gingivitis that has been found in Alzheimer's patients.
Here [4] is a paper on the gingivalis hypothesis funded by Cortexyme.
It's a small molecule that targets gingipains, cysteine proteases of the P. gingivalis, a periodontal pathogen responsible for gingivitis that has been found in Alzheimer's patients.
Here [4] is a paper on the gingivalis hypothesis funded by Cortexyme.
[1] https://clinicaltrials.gov/ct2/show/NCT03823404?term=NCT0382...
[2] https://gaintrial.com/en/about
[3] https://www.cortexyme.com/?page_id=6022
[4] https://advances.sciencemag.org/content/5/1/eaau3333