The arch linux wiki page [1] is a good place to start (Note you don't have to use arch for the host to get value out of the page, I use nixos), and/or the macos repo [2] (Or maybe this newer one [3])

The only real hurdle hardware wise is your IOMMU groups and your CPU compatibility, if you have a moderately modern system it should be a problem.

I also have a couple of inexpensive PCIe USB cards that I pass through to the guests for direct USB access, highly recommended.

The guides will use qcow2 images or pass through a block device, as I mentioned I have a giant LVM pool, I just create lvs for each vm and pass the volume through to the vm as a disk , and let the vm handle it. In the host you can use kpartx to bind and mount the partitions if you ever need to open them up.

[1] https://wiki.archlinux.org/index.php/PCI_passthrough_via_OVM...

[2] https://github.com/kholia/OSX-KVM

[3] https://github.com/yoonsikp/macos-kvm-pci-passthrough