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Re:Single dose of psilocybin eased cancer patients' anxiety,... by pmoriarty on Tuesday January 28, 2020 @12:44PM (#22171821)
"If the single-dose effect for cancer patients really is this strong, it seems like everyone who messed with mushrooms once in college should be 'treated' also."

Set, drug, dose, and setting all play huge roles in the effects one gets.

First, a lot of drugs on the black market aren't what they claim to be. So someone who tried what they thought were mushrooms in college might have gotten something else.

The dose of psilocybin one gets from black market mushrooms is also difficult if not impossible to gauge. So someone who tried mushrooms in college could have gotten too low or too high a dose.

Many people are also completely clueless when it comes to how to optimally prepare for and take drugs, and believe all sorts of myths and misconceptions about drugs. So many of those who took mushrooms in college probably did so in very poor circumstances, with no intention or even self-destructive intentions (such as those that often go hand-in-hand in binge-drinking), and possibly with misconceptions about what the experience will be like.

This is all very, very different from taking psilocybin or other psychedelics in a carefully designed study, with trained therapists who typically give days if not weeks of therapy before the sessions, during, and after the sessions, are given pure, precisely measured doses. The setting is designed for maximum therapeutic effect, as are the resources available during the session (such as having pictures of loved-ones on hand to focus on at the peak of the session). The sessions are usually done with light blocked out by an eye-shade, and with music carefully designed to facilitate the session. The therapists are on hand to give support and help the patient work through any diffcult experiences, and are encouraged to work through such difficulties rather than run away from them. Acceptance is encouraged.

Because of this careful preparation, planning, and professional therapy, the results are likely to be much different than casual mushroom use in college by people who are likely to be ignorant of psychedelics in general, and of how to properly run a therapeutic session in particular.

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