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Re:23andMe lays off 100 people as DNA test sales decline by shoguning on Thursday January 23, 2020 @06:58PM (#22133776)
Exome could plausibly change due to alternative splicing, but my guess is that what is meant here is transcriptome, which is which genes are actually transcribed and their quantities.

Unfortunately RNA is chemically unstable. Not sure if cDNA synthesis could be done with a consumer kit.

Gut biome population sequencing/gene panels probably easier to get.

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