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Re:ADHD, a Lifelong Struggle (2018) by tcj_phx on Thursday January 23, 2020 @04:24PM (#22132272)
Stimulants have the adverse effect of harming the mitochondria/metabolism.

Most conditions improve when the metabolism is normalized. B-vitamins are pro-metabolic.

Sometimes doctors do good work. My girlfriend's doctors eventually figured out that she is a poor methylator, and can't convert folic acid into folate (Vitamin B-9). She therefore absolutely requires a dietary source of Folate, instead of the folic acid that is used to fortify many foods. She said this vitamin was profoundly helpful for her complaint of "depression".

Sometimes doctors make work for themselves. Using Stimulants to treat metabolic problems is an exercise in futility.

Re:ADHD, a Lifelong Struggle (2018) by eq_sd_ on Thursday January 23, 2020 @04:56PM (#22132639)
I can say the opposite. I have the MTHFR mutation and ADHD. Taking vitamins did not alleviate my ADHD symptoms.
Re:ADHD, a Lifelong Struggle (2018) by firediamond on Thursday January 23, 2020 @10:14PM (#22135084)
Do you have any insight into how, exactly, those doctors figured that out? What kind of specialists?
Re:ADHD, a Lifelong Struggle (2018) by tcj_phx on Thursday January 23, 2020 @10:54PM (#22135261)
Deplin [0] is a patented prescription version of Vitamin B-9 aka L-Methylfolate. It's approved as an add-on treatment for when so-called antidepressants don't help with a person's symptoms. There's a genetic test that tells if a person is a poor methylator who especially needs Folate instead of folic acid.

I don't know how they decided to run the genetic test, I just heard that they did and that folate really helps her. She eventually switched to non-prescription folate (from the supplement aisle), probably mostly because of cost, or maybe some other reason.

Folate is cheap enough to experiment with: if you notice something dramatic, keep taking it.

[0] https://deplin.com/what-is-deplin