There's obviously no guarantee in the long run, but Gabriel Weinberg (DDG founder) is arguably one of the most holistic tech founders when it comes to tackling socially impactful problems in tech probably due to his interdisciplinary background. He's detailed his approach in a variety of podcasts and blog posts over the years

https://medium.com/@yegg/mental-models-i-find-repeatedly-use...

https://fs.blog/gabriel-weinberg/