Uh, my work device is a laptop and I use multi-large-monitors. With external keyboard and mouse.

I can unplug it (single cable) and take to a conference room if the need arises. I can take off early and plug it at home. It has a built-in UPS by the virtue of having a battery. Why would a desktop be better, unless you need crazy hardware?

I do have a desktop at home, but that's for my personal uses.