No, I haven't really tried it. I know that it exists and that there are people who like it, but making everything work under Windows is a hassle I haven't bothered going through. (Basically I would have to write an Emacspeak-compatible speech server that would use Windows's TTS for speaking.) It could also be that Emacs and braille wouldn't work very well together in Windows, but this is also something I haven't really explored.