On the Free side, I think one reason is the copyleft nature of the GPL. Another pattern indicator is how modular the software is - smaller bits are easier to open source than massive projects - and the general inclinations of the programmers, their bosses, and their legal teams.
That being said, I don't think it's unreasonable to expect a Free alternative to AutoCAD in 2020. (Pipes 3D is an AutoCAD extention). It's widely used software across numerous industries, much like Photoshop, Illustrator or Audition, but there is no Free alternative that I'm aware of.
A particularly annoying thing to me here is that AVEVA was actually originally developed and owned by the British government, but it was privatized (I think under Thatcher.) I think the value created for the tax payer would have been much greater to create free tools and software and make them available to everybody rather than just whatever pittance they got from selling it during a privatization firesale.
Another exception is public works paid by taxes such as Government open source projects.
And yet, in commercial industry where I've worked - it is hard to find anything that's useful and can replace internal software because there are no free alternatives. I don't expect these things to be out and open!
They're niche industries that require tremendous amount of upfront investment, in both physical assets to realize the utility of the open-source project, and knowledge-base required to operate the software.
On the other hand, you could have a piece of software that requires niche knowledge but its used literally everywhere - for e.g. OpenSSL. Not many people can contribute to it, yet it exists as open source. The point I am trying to make is that OpenSSL and your quantum hardware control software are very different things.