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Re:Rapidly cooling trauma victims to buy more time for surgery by DennisP on Wednesday November 20, 2019 @04:13PM (#21588577)
Seems like a combination approach might help. Even if a carrier isn't good enough at body temperature, it might extend viability when chilled, compared to just using saline.
Re:Rapidly cooling trauma victims to buy more time for surgery by justinclift on Wednesday November 20, 2019 @05:16PM (#21589181)
Wonder how feasible it'd be to er... super saturate "stock" blood (eg from blood packs) with extra oxygen carrying red blood cells? Preferably oxygenated just prior to being used for this.
Re:Rapidly cooling trauma victims to buy more time for surgery by rtkwe on Wednesday November 20, 2019 @05:30PM (#21589310)
Doesn't really help if the path to the brain is leaking like a sieve. Also one of the goals with blood substitutes was to make them physically smaller than red blood cells to get past the second issue which is swelling that can restrict blood supplies. The idea was a smaller O2 carrying molecule could squeeze through where a red blood cell couldn't.