They aren't perfect, as they tend to amplify sounds from within your own body; I can't drink or eat with them in. However, they are still light-years better than dealing with random throat clearing and chewing.

I really want one of those egg shaped sound-blocking chairs for work. I read in a wing-back chair and it's amazing how much sound deadening it provides.

I get the 3M EAR classic superfit 33s in boxes of 250. Makes a huge difference in my life.

Seconded. I actually use the EAR Classic Plus, and they’re excellent.

I work in a coworking space. They’re not quite comfortable enough to wear continuously all day. If you take periodic breaks, and remove them when you go to the bathroom, get coffee, take a walk, that’s enough make it so you can keep them in while working at your desk.

Breaks are good so I don’t really count this as a negative.

They even perform well in super noisy coffee shops.

Thanks for the suggestion! I'll have to check them out. I use the Howard Leight MAX-1 and they're very comfortable.