https://en.wikipedia.org/wiki/Embraer_E-Jet_E2_family#E195-E...
https://en.wikipedia.org/wiki/Airbus_A220#/media/File:CSerie...
I think what's missing in the Airbus-Boeing debate is an appreciation for the role of engine manufacturers. The A220, E195-E2, and Mitsubishi SpaceJet are all built around P&W's new geared turbofan engines.
It seems to me that at this point in the evolution of the industry everybody effectively builds their planes around the capabilities and limits of available engine technology. The immediate cause of death of the A380 was the refusal of any engine manufacturer to design and sell a more modern engine. The A380 became inefficient because its engines were at least 1.5 generations behind, not because there were 4 of them. (Of course, the reason nobody wanted to invest in a newer engine was because the market was too small to make it worth their time, especially considering their struggles with existing commitments.)
I imagine any aerospace engineering company could design a state-of-the-art and competitive body around the available engines. Aircraft manufacturers seem to self-select into market niches not because of engineering costs and difficulties, but simply because the global markets aren't large enough to support a third wide body manufacturer and only barely large enough, if at all, to support another 737/A320.
Embraer's commercial business is owned by Boeing now — the subsidiary is called BBC.
Personally, I'd like to see Mitsubishi get back into the passenger plane business. They're already starting, but with a smaller regional jet.