I think there are workarounds to get from the tmux copy buffer onto the system clipboard but I usually just `Ctrl-b z` to zoom the pane to full-screen, hold down `fn` button to select text, then `Ctrl-C` like normal.
bind-key -T copy-mode-vi Enter send-keys -X copy-pipe-and-cancel "pbcopy"
bind-key -T copy-mode-vi C-j send-keys -X copy-pipe-and-cancel "pbcopy"
bind-key -T copy-mode-vi MouseDragEnd1Pane send-keys -X copy-pipe-and-cancel "pbcopy"
bind-key -T copy-mode-vi A send-keys -X append-pipe-and-cancel "pbcopy"1. If I click my mouse to drag and select what I want to copy, the selection is copied to the clipboard when I release. Selection is highlighted with a yellow background.
2. If I want to double-click to copy, I just hold down the `option` key, then double click and it is copied to the clipboard. Selection is highlighted with a white background.
In both instances, I don't even need to use `ctrl+c`.
You may not way to scroll by accident if your application can use scrolling for changing commands like psql
You may want to do mouse scroll only if you initiated scrolling with say Shift+Page Up
(for me, all the above)